Research programme: GPR119 protein agonists - Metabolex

Drug Profile

Research programme: GPR119 protein agonists - Metabolex

Latest Information Update: 20 Dec 2013

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At a glance

  • Originator Metabolex
  • Developer CymaBay Therapeutics
  • Class Small molecules
  • Mechanism of Action GPR119 protein agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Type 2 diabetes mellitus

Most Recent Events

  • 10 Dec 2013 Discontinued - Preclinical for Type-2 diabetes mellitus in USA (PO)
  • 28 Apr 2011 GPR119 protein agonists are no longer licensed to sanofi-aventis worldwide
  • 28 Jun 2010 Metabolex and sanofi-aventis enter into a global licensing agreement for discovery, development, manufacture and commercialisation of small molecule GPR 119 agonists for the treatment of type 2 diabetes ,
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