Prexigebersen

Drug Profile

Prexigebersen

Alternative Names: BP 100-1-01; BP-100-1.01; BP-1001; L-Grb-2; L-Grb-2 antisense; Liposomal Grb-2 antisense; Liposomal Grb2 antisense oligonucleotide

Latest Information Update: 27 Jan 2017

$50 / €47 *
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At a glance

  • Originator University of Texas M. D. Anderson Cancer Center
  • Developer Bio-Path Holdings
  • Class Antineoplastics; Antisense oligonucleotides; Nucleotides
  • Mechanism of Action Extracellular signal-regulated MAP kinase inhibitors; GRB2 adaptor protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic myeloid leukaemia; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I Acute lymphoblastic leukaemia; Chronic myeloid leukaemia; Myelodysplastic syndromes
  • Preclinical Breast cancer; Colorectal cancer; Head and neck cancer; Lymphoma; Solid tumours; Thyroid cancer

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 03 Dec 2016 Pharmacodynamics data from a phase I trial in Chronic myeloid leukemia presented at the 58th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2016)
  • 03 Nov 2016 BP 100-1-01 receives Orphan Drug status for Acute myeloid leukaemia in European Union
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