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Remetinostat - Medivir AB

Drug Profile

Remetinostat - Medivir AB

Alternative Names: Remetinostat gel 1%; SHAPE; SHP-141; SHP-141C; Suberohydroxamic acid phenyl ester

Latest Information Update: 29 Nov 2021

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At a glance

  • Originator Dana-Farber Cancer Institute; Harvard University
  • Developer Medivir AB; Shape Pharmaceuticals; Stanford University School of Medicine
  • Class Antineoplastics; Antipsoriatics; Benzoic acids; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T-cell lymphoma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Basal cell cancer; Cutaneous T-cell lymphoma

Highest Development Phases

  • Phase II Basal cell cancer; Cutaneous T-cell lymphoma; Squamous cell cancer
  • Discontinued Plaque psoriasis

Most Recent Events

  • 18 Nov 2021 Updated efficacy data from a phase II trial in Squamous cell cancer was released by Medivir
  • 16 Aug 2021 Medivir AB restructures agreement with TetraLogic Pharmaceuticals Corporation and The Leukemia & Lymphoma Society for remetinostat in the treatment of cutaneous T-cell lymphoma and other types of skin cancers
  • 12 Aug 2021 Efficacy and safety data from phase II trial in Basal cell cancer released by Medivir
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