Drug Profile


Alternative Names: SHAPE; SHP-141; SHP-141C; Suberohydroxamic acid phenyl ester (SHAPE)

Latest Information Update: 02 Jan 2017

Price : $50

At a glance

  • Originator Dana-Farber Cancer Institute; Harvard University
  • Developer Medivir AB; Shape Pharmaceuticals
  • Class Antineoplastics; Benzoic acids; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T cell lymphoma
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cutaneous T cell lymphoma
  • Discontinued Plaque psoriasis

Most Recent Events

  • 02 Jan 2017 Chemical structure information added
  • 29 Dec 2016 Medivir acquires remetinostat from TetraLogic
  • 09 Dec 2016 SHP 141 is now called remetinostat
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