Drug Profile


Alternative Names: LFG-316; NOV-4

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator MorphoSys; Novartis
  • Class Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Complement C5 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Choroiditis; Dry age-related macular degeneration; Panuveitis; Paroxysmal nocturnal haemoglobinuria; Thrombotic microangiopathy; Wet age-related macular degeneration

Most Recent Events

  • 19 Jul 2017 Novartis Pharmaceuticals completes a drug-drug interaction phase I trial in USA (unspecified route) (NCT02878616)
  • 15 Dec 2016 Biomarkers information updated
  • 26 Aug 2016 Novartis Pharmaceuticals initiates a drug-drug interaction phase I trial in USA (unspecified route) (NCT02878616)
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