Drug Profile


Alternative Names: G-146034; GLPG-0634; GS-6034

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Galapagos NV
  • Developer Galapagos NV; Gilead Sciences
  • Class 2 ring heterocyclic compounds; Amides; Anti-inflammatories; Antirheumatics; Cyclopropanes; Pyridines; Small molecules; Thiamorpholines; Triazoles
  • Mechanism of Action Janus kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Crohn's disease; Rheumatoid arthritis; Ulcerative colitis
  • Phase II Ankylosing spondylitis; Cutaneous lupus erythematosus; Psoriatic arthritis; Sjogren's syndrome

Most Recent Events

  • 25 Apr 2017 Phase-II clinical trials in Cutaneous lupus erythematosus (Combination therapy, Treatment-experienced, In adults, In the elderly) in USA, Canada (PO)
  • 25 Apr 2017 Gilead Sciences and Galapagos plan a phase II proof-of-concept trial for Cutaneous lupus erythematosus (In adults, In the elderly, Combination therapy, Treatment-experienced) in USA and Canada (NCT03134222)
  • 11 Apr 2017 Phase-II clinical trials in Crohn's disease (In the elderly, In adults, Treatment-experienced) in Hungary (PO) (EudraCT2016-003179-23)
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