Drug Profile


Alternative Names: ARN-509; JNJ-56021927; JNJ-927

Latest Information Update: 24 Feb 2017

Price : $50

At a glance

  • Originator University of California System
  • Developer Case Comprehensive Cancer Center; Institut Paoli-Calmettes; Janssen Research & Development
  • Class Antiandrogens; Antihormones; Antineoplastics; Aza compounds; Benzamides; Pyridines; Small molecules; Spiro compounds; Sulfhydryl compounds; Thiohydantoins
  • Mechanism of Action Androgen receptor antagonists; Hormone inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Prostate cancer

Most Recent Events

  • 08 Feb 2017 Phase-II clinical trials in Prostate cancer (Early-stage disease) in France (PO) (EudraCT2016-001266-29)
  • 03 Jan 2017 Janssen Research & Development and Alliance Foundation Trials plan a phase III trial for Prostate cancer (Combination therapy, Recurrent, Second-line therapy or greater) in USA (PO, Tablet) (NCT03009981)
  • 16 Dec 2016 Instituto do Cancer do Estado de São Paulo and Janssen plan a phase II trial for Prostate cancer (Combination therapy, Neoadjuvant therapy, First-line therapy) in Brazil (PO) (NCT02789878)
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