Research programme: antibody-drug conjugates - Genmab/Seattle Genetics

Drug Profile

Research programme: antibody-drug conjugates - Genmab/Seattle Genetics

Alternative Names: HuMax-CD74-ADC

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator Genmab; Seattle Genetics
  • Class Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Axl receptor tyrosine kinase inhibitors; Immunomodulators; Mitosis inhibitors; Thromboplastin inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors; Tumour protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Solid tumours
  • No development reported Cancer

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for research development in Cancer in USA (Parenteral)
  • 10 Sep 2014 Genmab and Seattle Genetics enter into additional antibody-drug conjugate collaboration
  • 18 Jul 2013 Preclinical trials in Solid tumours in USA (Parenteral)
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