Drug Profile


Alternative Names: BMN-111; Modified C-natriuretic peptide; ProCNP38

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator BioMarin Pharmaceutical
  • Class Cyclic peptides; Natriuretic agents; Natriuretic peptides; Recombinant proteins
  • Mechanism of Action C-type natriuretic peptide stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Achondroplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Achondroplasia

Most Recent Events

  • 03 Mar 2017 Phase-II development is ongoing in Australia, United Kingdom, France and USA (SC)
  • 12 Dec 2016 Phase-III clinical trials in Achondroplasia (In adolescents, In children) in Australia (SC)
  • 27 Oct 2016 BioMarine Pharmaceutical plans an open-label extension study to a phase III trial in Achondroplasia (In children)
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