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Drug Profile

CUDC 427

Alternative Names: CUDC-427; GDC-0917; RG-7459

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Genentech
  • Class Amides; Antineoplastics; Oxazoles; Peptides; Pyrrolidines; Small molecules; Thiazoles
  • Mechanism of Action Inhibitor of apoptosis protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Lymphoma; Solid tumours

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Lymphoma(Late-stage disease, Second-line therapy or greater) in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Second-line therapy or greater) in USA (PO)
  • 01 Apr 2016 Curis completes a phase I trial in Solid tumours and lymphomas (second-line therapy or greater; late stage disease) in USA

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