Botulinum toxin A topical - Revance Therapeutics

Drug Profile

Botulinum toxin A topical - Revance Therapeutics

Alternative Names: BoNTA; DaxibotulinumtoxinA Topical gel; RT 001 - Revance; RT-001

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Revance Therapeutics
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants
  • Mechanism of Action Acetylcholine inhibitors; Glutamate-antagonists; Neuromuscular blocking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Migraine
  • Preclinical Neuropathic pain
  • Discontinued Facial-wrinkles; Hyperhidrosis

Most Recent Events

  • 04 Aug 2016 Revance Therapeutics has patent protection for botulinum toxin-related applications
  • 01 Aug 2016 Revance Therapeutics completes the phase III REALISE 1 trial in Facial wrinkles in USA (NCT02580370)
  • 13 Jun 2016 Discontinued - Phase-II for Hyperhidrosis in USA as the phase III Realise 1 trial failed to achieve its primary endpoint (Topical)
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