Drug Profile


Alternative Names: GS-9451; VDV

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Gilead Sciences
  • Class Amides; Antivirals; Carbamates; Carboxylic acids; Cyclopentanes; Cyclopropanes; Hydroxyquinolines; Macrocyclic compounds; Morpholines; Pyrrolidines; Thiazoles
  • Mechanism of Action Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis C

Most Recent Events

  • 01 Feb 2015 Gilead Sciences completes a phase II trial for Hepatitis C (Combination therapy) in USA (NCT02226549)
  • 07 Oct 2014 Gilead Sciences completes enrolment in a phase II trial in Hepatitis C (Combination therapy) in USA (NCT02226549)
  • 01 Jul 2014 Phase-II clinical trials in Hepatitis C (Combination therapy, Treatment-experienced) in USA (PO)
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