Research programme: neurodegenerative disease therapeutics - ProMIS Neurosciences

Drug Profile

Research programme: neurodegenerative disease therapeutics - ProMIS Neurosciences

Alternative Names: PMN 350; PMN-310; TDP 43 targeting therapeutics

Latest Information Update: 08 Jun 2017

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At a glance

  • Originator Amorfix Life Sciences
  • Developer ProMIS Neurosciences
  • Class Antidementias; Monoclonal antibodies; Neuroprotectants
  • Mechanism of Action Amyloid beta-protein modulators; Superoxide dismutase inhibitors; Tau protein inhibitors; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Neurodegenerative disorders

Highest Development Phases

  • Preclinical Alzheimer's disease; Amyotrophic lateral sclerosis; Dementia
  • Research Down syndrome

Most Recent Events

  • 31 May 2017 Preclinical trials in Dementia in Canada (Parenteral)
  • 30 May 2017 ProMIS Neurosciences files for patent protection with USPTO for epitope target on misfolded forms of TDP43 in USA
  • 24 May 2017 Pharmacodynamics data from preclinical studies in Alzheimer's disease released by ProMIS Neurosciences
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