Research programme: cancer and inflammation therapeutics - Xcovery

Drug Profile

Research programme: cancer and inflammation therapeutics - Xcovery

Alternative Names: X-339; X-376; X-379; X-414; X-480

Latest Information Update: 06 Oct 2016

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At a glance

  • Originator Xcovery
  • Developer Xcovery Holdings
  • Class Pyrazolones; Pyrimidines; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Hepatocyte growth factor inhibitors; MTOR protein inhibitors; P38 mitogen-activated protein kinase inhibitors; Vascular endothelial growth factor receptor 3 antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Preclinical Cancer
  • Discontinued Inflammation

Most Recent Events

  • 05 Oct 2016 Discontinued for Inflammation in USA (PO)
  • 05 Oct 2016 Preclinical development is ongoing for cancer in USA (Xcovery pipeline, October 2016)
  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in USA (PO)
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