Drug Profile


Alternative Names: CLS 008; M-5180; M-518101

Latest Information Update: 14 Jun 2017

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At a glance

  • Originator Maruho
  • Class Acetamides; Anti-inflammatories; Fluorocarbons; Indenes; Skin disorder therapies; Small molecules; Vitamin D analogues
  • Mechanism of Action Phosphoric diester hydrolase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Palmoplantar keratoderma; Plaque psoriasis

Most Recent Events

  • 01 Mar 2017 Maruho completes a phase III trial in Palmoplantar keratoderma and Plaque psoriasis in Japan (Topical) (JapicCTI-152947)
  • 17 Nov 2016 Cutanea Life Sciences plans a phase II trial for Plaque psoriasis (In adolescents) in USA (NCT02970331)
  • 20 Apr 2016 Maruho completes a phase III trial for Plaque psoriasis in Japan (Topical) before April 2016 (JapicCTI-152946)
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