Research programme: small molecule therapeutics - Quimatryx

Drug Profile

Research programme: small molecule therapeutics - Quimatryx

Alternative Names: DNA methyltransferase inhibitors - Quimatryx; DNMT inhibitors - Quimatryx; HDAC inhibitors - Quimatryx; HDAC2 selective inhibitor - Quimatryx; HDAC6 selective inhibitor - Quimatryx; Isoform selective HDAC inhibitor - Quimatryx; JMJ inhibitors - Quimatryx; JMJ2DC(GASC1) inhibitors - Quimatryx; LFA-1 integrin inhibitor - Quimatryx; Lymphocyte function-associated antigen-1 inhibitor - Quimatryx; Proteasome inhibitors - Quimatryx; QTX 100; QTX 125; QTX 153; QTX 200; QTX 300; QTX 400; Sirtuin inhibitors and activators - Quimatryx

Latest Information Update: 31 Oct 2017

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At a glance

  • Originator IkerChem
  • Developer Quimatryx
  • Class Antidementias; Antineoplastics; Neuroprotectants; Small molecules
  • Mechanism of Action DNA methylation inhibitors; HDAC6 protein inhibitors; Jumonji domain-containing histone demethylase inhibitors; Lymphocyte function-associated antigen-1 inhibitors; Methyltransferase inhibitors; Proteasome inhibitors; Sirtuin inhibitors; Sirtuin stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer; CNS disorders
  • Discontinued Liver metastases

Most Recent Events

  • 31 Oct 2017 Discontinued - Preclinical for Liver metastases in Spain (Quimatryx pipeline, October 2017)
  • 17 Aug 2016 Preclinical development is ongoing for Cancer [PO] and CNS disorders [PO] in Spain (Quimatryx pipeline, August 2016)
  • 16 Jul 2016 No recent reports of development identified for preclinical development in Cancer in Spain (PO)
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