Drug Profile


Alternative Names: Ad5/3-D24-GMCSF; CGTG-102; ONCOS-102

Latest Information Update: 22 Feb 2017

Price : $50

At a glance

  • Originator Oncos Therapeutics
  • Developer Oncos Therapeutics; Targovax
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma; Mesothelioma; Ovarian cancer
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Mesothelioma
  • Phase I Malignant melanoma; Ovarian cancer; Soft tissue sarcoma
  • Preclinical Prostate cancer
  • No development reported Solid tumours

Most Recent Events

  • 21 Nov 2016 Targovax and MedImmune plan a phase I/II trial for Colorectal cancer and Ovarian Cancer (Combination therapy, Second-line therapy or greater) in USA (NCT02963831)
  • 14 Oct 2016 Targovax suspends a phase-I/II trial in Mesothelioma (Combination therapy, Inoperable/Unresectable) in Spain (EudraCT2015-005143-13) prior to October 2016
  • 25 Aug 2016 Targovax intends to initiate four new clinical trials
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