Drug Profile


Alternative Names: Ad5/3-D24-GMCSF; CGTG-102; ONCOS-102

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator Oncos Therapeutics
  • Developer Ludwig Institute for Cancer Research; MedImmune; Oncos Therapeutics; Targovax
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma; Ovarian cancer; Mesothelioma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Colorectal cancer; Mesothelioma; Ovarian cancer
  • Phase I Malignant melanoma; Soft tissue sarcoma
  • Preclinical Prostate cancer
  • No development reported Solid tumours

Most Recent Events

  • 07 Sep 2017 Phase-I/II clinical trials in Colorectal cancer (Combination therapy, Second-line therapy or greater) in USA (Intraperitoneal) (NCT02963831)
  • 07 Sep 2017 Phase-I/II clinical trials in Ovarian cancer (Second-line therapy or greater, Combination therapy) in USA (Intraperitoneal) (NCT02963831)
  • 21 Nov 2016 Targovax and MedImmune plan a phase I/II trial for Colorectal cancer and Ovarian Cancer (Combination therapy, Second-line therapy or greater) in USA (NCT02963831)
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