CM 2489

Drug Profile

CM 2489

Alternative Names: CCI; CM-2489; CRAC channel inhibitor - CalciMedica

Latest Information Update: 17 Nov 2016

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At a glance

  • Originator CalciMedica
  • Class Antipsoriatics; Small molecules
  • Mechanism of Action Immunosuppressants; ORAI1 protein inhibitors; STIM1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Plaque psoriasis

Most Recent Events

  • 17 Nov 2016 Discontinued - Phase-I for Plaque psoriasis in USA (PO) before November 2016 (CalciMedica's website, November 2016)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Plaque-psoriasis in USA (PO)
  • 17 Feb 2011 Phase-I clinical trials in Plaque psoriasis (in volunteers) in USA (PO)
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