Drug Profile


Alternative Names: DE-111; Tafluprost/timolol maleate; TAPCOM; Taptiqom; Timolol maleate/tafluprost; Timolol/tafluprost

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Santen Oy; Santen Pharmaceutical
  • Developer Asahi Glass; Santen Oy; Santen Pharmaceutical
  • Class Amino alcohols; Antiglaucomas; Antihypertensives; Ischaemic heart disorder therapies; Morpholines; Propanolamines; Prostaglandins; Small molecules; Thiadiazoles
  • Mechanism of Action Beta-adrenergic receptor antagonists; Prostaglandin F2 alpha agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Glaucoma; Ocular hypertension

Most Recent Events

  • 01 Dec 2016 Santen Pharmaceutical completes a phase II trial for Open angle glaucoma and Ocular hypertension in Japan (Ophthalmic) (UMIN000016052)
  • 09 Sep 2016 Launched for Ocular hypertension and Glaucoma in Estonia (Ophthalmic) before September 2016
  • 10 Aug 2016 Santen Pharmaceutical initiates a clinical trial for Open angle glaucoma in Japan (Ophthalmic) (UMIN000023883)
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