Drug Profile


Alternative Names: ACT-334441; lysosphingolipid receptor agonist - Actelion; S1P1 receptor modulator - Actelion; Second selective S1P1 receptor agonist - Actelion; Sphingosine 1 phosphate receptor modulators - Actelion; Sphingosine 1-phosphate receptor 1 agonists - Actelion

Latest Information Update: 20 Mar 2017

Price : $50

At a glance

  • Originator Actelion Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Lysosphingolipid receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Systemic lupus erythematosus

Most Recent Events

  • 22 May 2017 Actelion Pharmaceuticals plans a phase III trial for Systemic lupus erythematosus
  • 01 Feb 2017 Actelion completes a phase I/II trial in Systemic lupus erythematosus in Georgia, Russia, USA, Bulgaria, Ukraine, Belarus (PO) (NCT02472795)
  • 01 Dec 2016 Actelion completes a phase I trial in Systemic lupus erythematosus (In volunteers) in Netherlands (PO) (NCT02914223)
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