Drug Profile


Alternative Names: CM-082; X-82

Latest Information Update: 12 Jun 2017

Price : $50

At a glance

  • Originator Tyrogenex
  • Developer AnewPharma; Tyrogenex; Washington University School of Medicine
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Platelet-derived growth factor beta receptor antagonists; Vascular endothelial growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Age-related macular degeneration
  • Phase I/II Pancreatic cancer
  • Phase I Renal cell carcinoma
  • No development reported Solid tumours

Most Recent Events

  • 08 Jun 2017 Adverse events data from a phase I/II trial in Age-related macular degeneration released by Tyrogenex
  • 31 Mar 2017 AnewPharma plans a phase II/III trial for Renal cell carcinoma(Metastatic disease, Combination therapy) in China (NCT03095040)
  • 30 Mar 2017 Chemical structure information added
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