PRX 106

Drug Profile

PRX 106

Alternative Names: Anti-TNF therapeutic - Protalix Biotherapeutics; Anti-tumour necrosis factor therapeutic - Protalix Biotherapeutics; OPRX 106; pr-anti-TNF; PRX-106

Latest Information Update: 24 May 2017

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At a glance

  • Originator Protalix Biotherapeutics
  • Developer Protalix BioTherapeutics
  • Class Recombinant fusion proteins
  • Mechanism of Action Interferon gamma inhibitors; Interleukin 10 stimulants; Regulatory T-lymphocyte stimulants; Tumour necrosis factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Inflammatory bowel diseases

Highest Development Phases

  • Phase II Ulcerative colitis
  • Preclinical Autoimmune disorders; Crohn's disease; Fatty liver; Hepatitis; Inflammatory bowel diseases; Non-alcoholic steatohepatitis; Rheumatoid arthritis

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 30 Nov 2016 Protalix initiates enrolment in a phase II trial for Ulcerative colitis in Israel (PO)
  • 01 Sep 2016 Phase-II clinical trials in Ulcerative colitis in Israel (PO) (NCT02768974)
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