Drug Profile


Alternative Names: TSR-011

Latest Information Update: 31 Jul 2017

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At a glance

  • Originator Amgen
  • Developer TESARO
  • Class Antineoplastics; Benzamides; Benzimidazoles; Piperidines; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; Tropomyosin-related kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Lymphoma; Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 31 Jul 2017 Chemical structure information added
  • 14 Jul 2015 TSR 011 is still in phase I/II trials for Solid tumours, Non-small cell lung cancer and Lymphoma in USA and United Kingdom
  • 14 Jul 2015 Phase-I/II clinical trials in Solid tumours, Non-small cell lung cancer and Lymphoma in Poland, Spain, Taiwan (PO)
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