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Rivogenlecleucel - Bellicum Pharmaceuticals

Drug Profile

Rivogenlecleucel - Bellicum Pharmaceuticals

Alternative Names: Allogeneic polyclonal T-cells - Bellicum Pharmaceuticals; BPX-501; BPX-501 and AP1903; BPX-501-AP1903; BPX-501-rimiducid; BPX-501-T-cells; CaspaCIDe® DLI; Rimiducid activated BPX 501; Rivo-cel; Rivo-cel - Bellicum Pharmaceuticals

Latest Information Update: 22 Mar 2024

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At a glance

  • Originator Bellicum Pharmaceuticals
  • Class Cell therapies; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease; Immunodeficiency disorders
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Acute myeloid leukaemia; Myelodysplastic syndromes
  • Phase I/II Haematological malignancies; Immunodeficiency disorders
  • No development reported Haemoglobinopathies; Immunological disorders; Metabolic disorders

Most Recent Events

  • 08 Mar 2024 Bellicum Pharmaceuticals terminates a phase I/II follow-up trial in Haematological malignancies (In infants, In children, In adolescents, In adults) in Italy (IV, Infusion) due to unknown reasons, before March 2024 (EudraCT2016-003226-16)
  • 28 Feb 2023 No recent reports of development identified for phase-I development in Haematological-malignancies(In adolescents, In children, In the elderly, In infants, Second-line therapy or greater, In adults) in USA (IV, Infusion)
  • 28 Mar 2021 No recent reports of development identified for phase-I development in Haematological-malignancies(In adolescents, In children, Recurrent) in Italy (IV, Infusion)
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