Drug Profile


Alternative Names: BPX-501; BPX-501 and AP1903; BPX-501-AP1903; BPX-501-rimiducid; CaspaCIDe; CaspaCIDe™ DLI; Rimiducid activated BPX 501

Latest Information Update: 10 Aug 2017

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At a glance

  • Originator Bellicum Pharmaceuticals
  • Class Cell therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunostimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease; Immunodeficiency disorders
  • New Molecular Entity No

Highest Development Phases

  • Phase II Haematological malignancies
  • Phase I/II Immunodeficiency disorders; Infections
  • Phase I Haemoglobinopathies; Immunological disorders; Metabolic disorders

Most Recent Events

  • 08 Aug 2017 Bellicum plans a registrational trial in Acute myeloid leukaemia (In adults) in USA
  • 23 Jun 2017 Efficacy and adverse events data from the phase II BP-004 trial in Haematological malignancies released by Bellicum
  • 23 Jun 2017 Updated efficacy and adverse events data from the phase I/II BP-004 trial in Haematological malignancies presented at the 22nd Congress of the European Haematology Association (EHA-2017)
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