Ivacaftor/tezacaftor

Drug Profile

Ivacaftor/tezacaftor

Alternative Names: Ivacaftor/VX 661; Tezacaftor/ivacaftor; VX-661/ivacaftor; VX-661/VX-770; VX-770/VX-661

Latest Information Update: 28 Apr 2017

Price : $50

At a glance

  • Originator Cystic Fibrosis Foundation Therapeutics; Vertex Pharmaceuticals
  • Class Amides; Aminophenols; Cyclopropanes; Fluorobenzenes; Quinolones; Small molecules
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator stimulants; Ion channel agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase III Cystic fibrosis

Most Recent Events

  • 28 Mar 2017 Vertex Pharmaceuticals announces intention to submit MAA to EMA for Cystic fibrosis in the third quarter of 2017
  • 28 Mar 2017 Vertex Pharmaceuticals announces intention to submit NDA to US FDA for Cystic fibrosis in the third quarter of 2017
  • 28 Mar 2017 Efficacy and adverse events data from two phase III trial in Cystic fibrosis released by Vertex Pharmaceuticals
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