Research programme: cancer diagnostics and therapeutics - Cellectar Biosciences

Drug Profile

Research programme: cancer diagnostics and therapeutics - Cellectar Biosciences

Alternative Names: 127I-CLR 1404; CLR 125; CLR 127; CLR 1401-boron-dipyrromethene analog; CLR 1404; CLR 1500 compounds - Cellectar Biosciences; CLR 1502; CLR 1601 PTX; CLR 1602; CLR 1602-PTX; CLR 1603; CLR 1603-PTX; CLR 1605-GEM; CLR 1700 series; CLR 1900 series; CLR 2000 series; CLR CTX; CLR1401; CLR1501; CLR1505; COLD; GLOW1; GLOW2; PDCs - Cellectar Biosciences; Phospholipid drug conjugates - Cellectar Biosciences; Phospholipid ether analogues - Cellectar Biosciences; PLEs - Cellectar Biosciences

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator University of Michigan Medical School
  • Developer Cellectar Biosciences
  • Class Drug conjugates; Imaging agents; Phospholipids; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; Apoptosis modulators; CD244 antigen modulators; CD8 positive T lymphocyte modulators; Cell division modulators; DNA synthesis inhibitors; Gene modulators; Histone deacetylase inhibitors; Proto oncogene protein c-akt inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer; Solid tumours

Most Recent Events

  • 30 Oct 2017 Preclinical data for CLR 127 in Cancer presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2017 (AACR-NCI-EORTC-2017)
  • 17 Oct 2017 Cellectar Biosciences has patent protection for CLR 125 in Japan
  • 01 Aug 2017 Cellectar Biosciences entered into a collaborative agreement with Avicenna Oncology for the development of phospholipid drug conjugates
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