Crizanlizumab

Drug Profile

Crizanlizumab

Alternative Names: SEG 101; Sel G1

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Selexys Pharmaceuticals
  • Developer Novartis
  • Class Monoclonal antibodies
  • Mechanism of Action P selectin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Sickle cell anaemia

Most Recent Events

  • 04 Aug 2017 Novartis plans a phase II trial for Sickle cell anaemia (In adults, In the elderly) (IV) (NCT03264989)
  • 31 May 2017 Novartis intends to make regulatory submissions seeking approval for Sickle cell anaemia in 2018
  • 03 Dec 2016 Efficacy and adverse events data from the SUSTAIN phase II trial in Sickle cell anaemia presented at the 58th Annual Meeting and Exposition of the American Society of Haematology
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