Diacerein - TWi Biotechnology

Drug Profile

Diacerein - TWi Biotechnology

Alternative Names: AC-201; AC-201 Controlled release tablet; AC-201CR; AC-203; CCP 020

Latest Information Update: 11 Dec 2017

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At a glance

  • Originator TWi Biotechnology; TWi Pharmaceuticals
  • Developer Castle Creek Pharmaceuticals; TWi Biotechnology
  • Class Anthraquinones; Anti-inflammatories; Antihyperglycaemics; Antirheumatics; Small molecules
  • Mechanism of Action Caspase 1 inhibitors; Interleukin 1 beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Epidermolysis bullosa
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Epidermolysis bullosa
  • Phase II Bullous pemphigoid; Gout; Joint disorders; Type 2 diabetes mellitus
  • Discontinued Diabetic nephropathies

Most Recent Events

  • 06 Dec 2017 Castle Creek Pharmaceuticals plans a phase II trial in Epidermolysis Bullosa in Netherlands (Topical) (EudraCT2017-003757-41)
  • 01 Nov 2017 Positive efficacy data from a phase II trial in Gout released by TWi Biotechnology
  • 05 Sep 2017 Phase-II clinical trials in Bullous pemphigoid in Taiwan (Topical) (NCT03286582)
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