Drug Profile


Alternative Names: ATL-313; DE-112

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Adenosine Therapeutics
  • Developer PGxHealth; Santen Pharmaceutical
  • Class Anti-inflammatories; Purine nucleosides; Small molecules
  • Mechanism of Action Adenosine A2A receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Glaucoma; Haematological malignancies; Multiple sclerosis; Neuropathic pain; Ocular hypertension

Most Recent Events

  • 01 Jul 2014 Forest Laboratories has been acquired by Actavis Inc
  • 01 Feb 2012 Santen completes the phase I/II trial in Glaucoma in USA (NCT01279083)
  • 01 Feb 2012 Santen completes the phase I/II trial in Ocular hypertension in USA (NCT01279083)
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