Drug Profile


Alternative Names: Anti-frizzled receptor monoclonal antibody - OncoMed; Anti-Fzd receptor monoclonal antibody - OncoMed; anti-Fzd7; Anti-Fzd7 receptor monoclonal antibody - OncoMed; OMP-18R5

Latest Information Update: 20 Apr 2017

Price : $50

At a glance

  • Originator Bayer HealthCare Pharmaceuticals; OncoMed Pharmaceuticals
  • Developer OncoMed Pharmaceuticals
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Frizzled-receptor-antagonists; Stem cell inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Breast cancer; Non-small cell lung cancer; Pancreatic cancer

Most Recent Events

  • 10 Apr 2017 Bayer pharma terminates its option to licence for vantictumab with OncoMed Pharmaceuticals
  • 08 Mar 2017 OncoMed Pharmaceuticals intends to submit data package for Vantictumab to Bayer for opt-in consideration in the first half of 2017
  • 10 Oct 2016 Efficacy and adverse events data from a phase Ib trial in Pancreatic cancer presented at the European Society of Medical Oncology (ESMO-2016) Congress
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