Drug Profile


Alternative Names: FYX-051; SK-0910; Topiroric; Uriadec

Latest Information Update: 01 May 2015

Price : $50

At a glance

  • Originator Fuji Yakuhin
  • Developer Fuji Yakuhin; Sanwa Kagaku Kenkyusho
  • Class Nitriles; Pyridines; Small molecules; Triazoles
  • Mechanism of Action Xanthine dehydrogenase inhibitors; Xanthine oxidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gout; Hyperuricaemia
  • Phase II Diabetic nephropathies

Most Recent Events

  • 01 Mar 2015 Phase-II clinical trials in Diabetic nephropathies in Japan (PO) (NCT02327754)
  • 01 Mar 2015 Sanwa Kagaku Kenkyusho and Fuji Yakuhin initiate enrolment in a phase II trial for Gout in Japan (NCT02327754)
  • 24 Dec 2014 Sanwa Kagaku Kenkyusho and Fuji Yakuhin plan a phase IIa trial in patients with diabetic nephropathy and hyperuricaemia, with or without Gout, in Japan (NCT02327754)
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