SM 101

Drug Profile

SM 101

Alternative Names: BAX 1810; FcγRIIb; Human soluble Fc-gamma receptor IIb - Shire; SHP 652; SM-101

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator SuppreMol
  • Developer Baxalta; Shire
  • Class Immunoglobulin Fc fragments; Recombinant proteins
  • Mechanism of Action Fc gamma receptor IIB modulators; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic thrombocytopenic purpura
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Idiopathic thrombocytopenic purpura; Systemic lupus erythematosus
  • No development reported Chronic obstructive pulmonary disease

Most Recent Events

  • 05 Sep 2017 SM 101 is still in phase II trials for Systemic lupus erythematosus (Shire pipeline, August 2017)
  • 05 Sep 2017 Shire plans a phase II trial for Systemic lupus erythematosus in third quarter of 2017 (Shire annual report, Form-10K,
  • 03 Jun 2016 Baxalta has been acquired and merged into Shire
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