Drug Profile


Alternative Names: AVI-7100; AVI-7376

Latest Information Update: 16 Jul 2016

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At a glance

  • Originator AVI BioPharma
  • Developer National Institute of Allergy and Infectious Diseases; Sarepta Therapeutics
  • Class Antisense oligonucleotides; Antivirals
  • Mechanism of Action Genetic transcription inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Influenza A virus infections

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for phase-I development in Influenza-A-virus-infections(In volunteers) in USA (IV, Infusion)
  • 01 Jun 2016 Sarepta Therapeutics and the National Institute of Allergy and Infectious Diseases complete a Phase-I trial for Influenza A virus infections (in volunteers) in USA (NCT01747148)
  • 30 Sep 2014 Sarepta completes a single ascending dose part of a phase I study in healthy volunteers; the Independent Data and Safety Monitoring Board recommends the study to continue as planned
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