Drug Profile


Alternative Names: HMPL-013

Latest Information Update: 08 Feb 2017

Price : $50

At a glance

  • Originator Hutchison MediPharma
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Vascular endothelial growth factor receptor 3 antagonists; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Colorectal cancer; Non-small cell lung cancer
  • Phase II Solid tumours
  • Phase I Gastric cancer

Most Recent Events

  • 17 Jan 2017 Hutchinson Medipharma completes the FRESCO phase III trial for Colorectal cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (NCT02314819)
  • 16 Jan 2017 Efficacy, adverse events and pharmacokinetics data from a phase Ib/II trial in Gastric cancer released by Hutchison MediPharma
  • 29 Nov 2016 Efficacy and adverse events data from a phase II trial in Non-small cell lung cancer released by Hutchison Medipharma
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