GDC 0425

Drug Profile

GDC 0425

Alternative Names: GDC-0425; RG-7602

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Genentech
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Checkpoint kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Lymphoma; Solid tumours

Most Recent Events

  • 01 May 2014 Genentech completes a phase I trial in Lymphoma and Solid tumours (late-stage disease) in USA and France (NCT01359696)
  • 30 Jan 2014 Discontinued - Phase-I for Lymphoma and Solid tumours (late-stage disease) in USA and France (PO)
  • 17 Oct 2013 GDC 0425 is still in phase I trials for Solid tumours and Lymphoma (late-stage disease) in USA and France
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