Baclofen/naltrexone/sorbitol

Drug Profile

Baclofen/naltrexone/sorbitol

Alternative Names: Baclofen/sorbitol/naltrexone; Naltrexone/baclofen/sorbitol; Naltrexone/sorbitol/baclofen; Pleocompound PXT3003; PXT-03003; PXT-3003; Sorbitol/baclofen/naltrexone; Sorbitol/naltrexone/baclofen

Latest Information Update: 21 Dec 2016

Price : $50

At a glance

  • Originator Pharnext
  • Class Aminobutyric acids; Analgesics; Antispastics; Cyclopropanes; Morphinans; Muscle relaxants; Small molecules; Sugar alcohols
  • Mechanism of Action GABA B receptor agonists; Opioid receptor antagonists; PMP22 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Charcot-Marie-Tooth disease
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Charcot-Marie-Tooth disease

Most Recent Events

  • 20 Dec 2016 Pharnext completes enrolment in the phase II PLEO CMT trial in Charcot-Marie-Tooth disease in USA, Belgium, Canada, France, Germany, Netherlands, Spain and United Kingdom
  • 17 Nov 2016 An independent Data Safety Monitoring Board recommends continuation of the phase III PLEO-CMT trial in Charcot-Marie-Tooth disease
  • 25 Apr 2016 Phase-III clinical trials in Charcot-Marie-Tooth disease (In adolescents, In adults) in USA (PO)
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