Drug Profile


Alternative Names: JNJ-3872; JNJ-63623872; JNJ-872; VX 787

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator Vertex Pharmaceuticals
  • Developer Janssen Pharmaceuticals; Vertex Pharmaceuticals
  • Class Antivirals; Pyridines; Pyrimidines; Pyrroles; Small molecules
  • Mechanism of Action Viral protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Influenza A virus infections

Most Recent Events

  • 23 Jun 2017 Efficacy and adverse event data from the phase IIb Topaz trial in Influenza-A virus infections released by Janssen Pharmaceuticals
  • 14 Jun 2017 Janssen Pharmaeuticals plans phase III trials for Influenza A in the second half of 2017
  • 06 Jun 2017 Janssen-Cilag International completes a phase I trial in Influenza-A virus infections (In volunteers) in Belgium (PO, Tablet) (IV) (NCT02860806)
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