Drug Profile


Alternative Names: Anti-NKG2A; IPH-2201; NN-8765; NNC 0141-0000-0100

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Innate Pharma; Novo Nordisk
  • Developer Innate Pharma; MedImmune; NCIC Clinical Trials Group; Novo Nordisk
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action NK cell lectin-like receptor subfamily C antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Head and neck cancer
  • Phase I/II Cervical cancer; Chronic lymphocytic leukaemia; Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase I Haematological malignancies; Solid tumours
  • Discontinued Inflammation; Rheumatoid arthritis

Most Recent Events

  • 01 Jan 2017 Innate Pharma terminates a phase II trial in Head and neck cancer (Late-stage disease, Metastatic disease, First-line therapy, Neoadjuvant therapy) in Spain and Germany due to lack of recruitment (IV) (NCT02331875)
  • 30 Nov 2016 Preliminary safety and efficacy data from a phase I/II trial in Ovarian cancer and Fallopian tube carcinoma released by Innate Pharma
  • 29 Nov 2016 Interim adverse events, PK, PD data from a phase I/II trial in Ovarian cancer and Fallopian tube carcinoma presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics (EORTC-NCI-AACR-2016)
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