Dianhydrogalactitol - DelMar Pharmaceuticals

Drug Profile

Dianhydrogalactitol - DelMar Pharmaceuticals

Alternative Names: DAG for Injection; Dianhydrodulcitol; Diepoxydulcitol; Diepoxygalactitol; NSC-1323313; VAL-083

Latest Information Update: 27 Nov 2017

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At a glance

  • Originator DelMar Pharmaceuticals
  • Developer DelMar Pharmaceuticals; Guangxi Wuzhou Pharmaceutical; National Cancer Institute (USA); University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Epoxy compounds; Ethylene glycols; Small molecules
  • Mechanism of Action Alkylating agents; Cell cycle inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma; Ovarian cancer; Medulloblastoma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Chronic myeloid leukaemia; Lung cancer

Highest Development Phases

  • Marketed Chronic myeloid leukaemia; Lung cancer
  • Phase III Glioblastoma
  • Clinical Phase Unknown Haematological malignancies; Solid tumours
  • Preclinical Medulloblastoma; Non-small cell lung cancer; Ovarian cancer

Most Recent Events

  • 21 Nov 2017 Pharmacodynamics data from a preclinical study in Glioblastoma released by DelMar Pharmaceuticals
  • 21 Nov 2017 Positive interim safety and efficacy data from a phase II trial in Glioblastoma released by DelMar Pharmaceuticals
  • 30 Oct 2017 Preclinical data in Cancer presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2017 (AACR-NCI-EORTC-2017)
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