Drug Profile


Alternative Names: CC 122

Latest Information Update: 21 Aug 2017

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At a glance

  • Originator Celgene Corporation
  • Class Antineoplastics
  • Mechanism of Action Signal transduction pathway modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Hepatocellular carcinoma
  • Phase I Glioblastoma; Multiple myeloma; Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 31 Jul 2017 Phase-I/II clinical trials in Diffuse large B cell lymphoma (Combination therapy, First-line therapy) in Spain (PO) (EudraCT2016-003778-42)
  • 05 Jul 2017 Avadomide licensed to BeiGene in China
  • 22 Jun 2017 Efficacy and adverse event data from a phase Ib trial in Non-Hodgkin's Lymphoma presented at the 22nd Congress of the European Haematology Association (EHA-2017)
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