Avadomide - Celgene Coporation

Drug Profile

Avadomide - Celgene Coporation

Alternative Names: CC 122

Latest Information Update: 03 Jan 2018

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At a glance

  • Originator Celgene Corporation
  • Class Antineoplastics; Piperidones; Quinazolines
  • Mechanism of Action Signal transduction pathway modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Hepatocellular carcinoma
  • Phase I Glioblastoma; Multiple myeloma; Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 08 Jan 2018 Celgene plans a pivotal programme for Non-Hodgkin lymphoma in 2018
  • 09 Dec 2017 Safety data from a phase I trial in Diffuse large B-cell lymphoma presented at the Annual Meeting and the Exposition of American Society for Haematology (ASH-2017)
  • 20 Nov 2017 Avadomide is still in phase I trials for Diffuse large B cell lymphoma (Combination therapy, Second-line therapy or greater) in USA, Canada, France and Italy (NCT02031419)
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