Anetumab ravtansine

Drug Profile

Anetumab ravtansine

Alternative Names: Anti-mesothelin antibody-drug conjugate BAY 94-9343; BAY-94-9343; BAY-94-9343-SPDB-DM4

Latest Information Update: 20 Jan 2017

Price : $50

At a glance

  • Originator Bayer HealthCare
  • Developer Bayer HealthCare; ImmunoGen; MorphoSys; National Cancer Institute (USA)
  • Class Antineoplastics; Immunoconjugates; Immunotoxins; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Lung cancer; Mesothelioma; Solid tumours
  • Phase I Non-small cell lung cancer; Ovarian cancer
  • Phase Unknown Pancreatic cancer

Most Recent Events

  • 13 Jan 2017 Investigation in Pancreatic cancer in USA (IV) before January 2017
  • 13 Jan 2017 Yale University and Bayer plan a phase II trial for Pancreatic cancer (Late-stage disease, Metastatic disease, Inoperable/Unresectable, Second-line therapy or greater) in USA (IV, Infusion) (NCT03023722)
  • 01 Sep 2016 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease) in USA (IV) (NCT02824042)
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