Drug Profile


Alternative Names: LGX-818; NVP-LGX818; NVP-LGX818-NXA; ONO-7702

Latest Information Update: 15 Jul 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Novartis Pharmaceuticals Corporation
  • Developer Array BioPharma; German Cancer Research Center; Novartis Pharmaceuticals Corporation; University of Heidelberg
  • Class Antineoplastics; Carbamates; Pyrazoles; Pyrimidines; Small molecules; Sulfonamides
  • Mechanism of Action Proto oncogene protein b raf inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Colorectal cancer; Malignant melanoma
  • Phase II Multiple myeloma; Solid tumours

Most Recent Events

  • 07 Aug 2017 European Organisation for Research and Treatment of Cancer plans a phase II trial for Malignant melanoma (Combination therapy, Inoperable/unresectable, Metastatic disease, Late-stage disease) (NCT03235245)
  • 02 Jun 2017 Efficacy and adverse events data from a phase I/II trial in Solid tumours (Combination therapy) presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 31 May 2017 Encorafenib licensed to Ono Pharmaceutical in Japan and South Korea
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top