Drug Profile


Alternative Names: CAT-1004; Docosahexaenoic acid-sodium salicylate conjugate; Sodium salicylate-docosahexaenoic acid conjugate

Latest Information Update: 04 May 2017

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At a glance

  • Originator Catabasis Pharmaceuticals
  • Developer Catabasis Pharmaceuticals; Sarepta Therapeutics
  • Class Anti-inflammatories; Antihyperglycaemics; Docosahexaenoic acids; Non-opioid analgesics; Salicylates; Small molecules
  • Mechanism of Action Inflammation mediator inhibitors; NF-kappa B inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Duchenne muscular dystrophy
  • Phase I Type 2 diabetes mellitus

Most Recent Events

  • 25 Apr 2017 Updated efficacy data from the phase I/II MoveDMD trial (Part B) in Duchenne Muscular Dystrophy reported at the 69th Annual Meeting of the American Academy of Neurology (AAN-2017)
  • 31 Jan 2017 Top-line efficacy and adverse events data from a phase I/II trial (Part B) in Duchenne Muscular Dystrophy released by Catabasis Pharmaceuticals
  • 21 Dec 2016 Chemical structure information added
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