Drug Profile


Alternative Names: H-1PV; ParvOryx; parvovirus H1

Latest Information Update: 08 Jun 2017

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At a glance

  • Originator German Cancer Research Center; University of Heidelberg
  • Developer Oryx GmbH & Co; University of Heidelberg
  • Class Antineoplastics; Oncolytic viruses
  • Mechanism of Action Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Pancreatic cancer
  • Phase I/II Glioblastoma

Most Recent Events

  • 23 May 2017 Efficacy and Safety data from compassionate use study in Glioblastoma released by ORYX (9217109; 3273406)
  • 10 Dec 2015 H 1PV is available for licensing as of 10 Dec 2015. http://www.oryx-medicine.com/
  • 15 Oct 2015 Phase-II clinical trials in Pancreatic cancer (Metastatic disease, Inoperable/Unresectable) in Germany (Intratumoural and IV) (EudraCT2015-001119-11)
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