RRx 001

Drug Profile

RRx 001

Alternative Names: RRx-001

Latest Information Update: 21 Sep 2017

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At a glance

  • Originator RadioRx
  • Developer EpicentRx
  • Class Antineoplastics; Azetidines; Nitro compounds; Small molecules
  • Mechanism of Action Free radical stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cholangiocarcinoma; Colorectal cancer; Neuroendocrine tumours; Non-small cell lung cancer; Small cell lung cancer
  • Phase I Glioblastoma; Glioma; Lymphoma; Solid tumours

Most Recent Events

  • 14 Feb 2017 Phase-I clinical trials in Glioblastoma and anaplastic Gliomas (Adjunctive treatment, Newly diagnosed, Late-stage disease) in USA (IV) (NCT02871843)
  • 12 Nov 2016 Preclinical data from studies in mice model were presented at the 89th Annual Scientific Sessions of the American Heart Association (AHA-2016)
  • 15 Aug 2016 EpicentRx plans the phase I G-FORCE-1 trial for Glioblastoma and Oligodendroglioma (Adjunctive treatment, Newly diagnosed, Late-stage disease) in USA (IV) (NCT02871843)
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