XmAb 5871

Drug Profile

XmAb 5871

Alternative Names: AMG 729; XmAb® 5871

Latest Information Update: 09 Nov 2017

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At a glance

  • Originator Xencor
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CD19 antigen inhibitors; Fc gamma receptor IIB modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Autoimmune disorders
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Autoimmune disorders; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 04 Nov 2017 Final adverse events, efficacy and pharmacodynamics data from a phase II trial in Autoimmune disorder released by Xencor
  • 04 Nov 2017 Xencor completes a phase II trial in Autoimmune disorders in USA
  • 04 Nov 2017 Xencor plans a phase III trial in IgG4-related disease in second half of 2018
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