MEDI 6469

Drug Profile

MEDI 6469

Alternative Names: Anti-OX40 monoclonal antibody; MEDI-6469

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator AgonOx; Providence Cancer Center
  • Developer MedImmune; Providence Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; OX40 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Breast cancer; Diffuse large B cell lymphoma; Prostate cancer; Solid tumours
  • Phase I Colorectal cancer; Head and neck cancer

Most Recent Events

  • 01 Apr 2016 MedImmune completes a phase I/II trial in Solid tumours and Diffuse large B cell lymphoma (Combination therapy, Late-stage disease) in USA (IV) (NCT02205333)
  • 16 Sep 2015 Phase-I/II development in solid tumours is ongoing in USA
  • 01 Sep 2015 Phase-I clinical trials in Colorectal cancer (Metastatic disease) in USA (IV) (NCT02559024)
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