Anti-GATA3 gene therapy - sterna biologicals

Drug Profile

Anti-GATA3 gene therapy - sterna biologicals

Alternative Names: Anti-GATA-3 gene therapy - sterna biologicals; hgd40; Human GATA-3-specific DNAzyme solution; SB 010; SB 011; SB 012

Latest Information Update: 07 Apr 2017

Price : $50

At a glance

  • Originator sterna biologicals; University of Marburg
  • Developer German Center for Lung Research; sterna biologicals
  • Class Anti-inflammatories; Antiasthmatics; Catalytic DNA; Gene therapies; Skin disorder therapies
  • Mechanism of Action GATA3 transcription factor inhibitors; Gene transference; Interleukin 13 expression inhibitors; Interleukin 4 expression inhibitors; Interleukin 5 expression inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Allergic asthma; Atopic dermatitis; Chronic obstructive pulmonary disease; Ulcerative colitis

Most Recent Events

  • 07 Apr 2017 Efficacy data from a Sub-group analysis of phase IIa trial in Allergic asthma released by Sterna biologicals
  • 01 Jan 2017 Sterna Biologicals completes a phase II trial in Atopic dermatitis in Germany (Topical) (NCT02079688)
  • 05 Aug 2015 Phase-II development is ongoing for Allergic asthma in Germany
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