AKB 9778

Drug Profile

AKB 9778

Alternative Names: AKB-9089; AKB-9778; AKB-9875; HPTP-beta mAb - Aerpio

Latest Information Update: 11 Feb 2016

Price : $50

At a glance

  • Originator Procter & Gamble
  • Developer Aerpio Therapeutics; Duke University; Harvard Medical School; Johns Hopkins University School of Medicine; Massachusetts General Hospital; Massachusetts Institute of Technology; Max Planck Institute for Molecular Biomedicine; New York University
  • Class Antihyperglycaemics; Small molecules
  • Mechanism of Action Angiopoietin modulators; Receptor-like protein tyrosine phosphatase inhibitors; TIE receptor agonists; TIE-2 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Diabetic macular oedema; Retinal vein occlusion
  • Preclinical Age-related macular degeneration; Breast cancer

Most Recent Events

  • 11 Feb 2016 Positive efficacy data from a phase IIa trial in Diabetic macular oedema released by Aerpio Therapeutics
  • 17 Nov 2015 Updated efficacy data from the phase IIa TIME 2 trial in Diabetic macular oedema (Adjunctive treatment, Monotherapy) released by Aerpio Therapeutics
  • 15 Jul 2015 Efficacy and adverse events data from the phase IIa TIME 2 trial in Diabetic macular oedema (Adjunctive treatment, Monotherapy) released by Aerpio Therapeutics
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